| Ausztrál Victoria League - U21 | 2022/04/16 05:00 | Melbourne Knights - U21 v Eastern Lions - U21 | W | 1-4 |
| Ausztrál Victoria League - U21 | 2021/05/23 03:00 | Melbourne Knights - U21 v Eastern Lions - U21 | D | 1-1 |
| Ausztrál Victoria League - U21 | 2022/07/08 08:15 | Bentleigh Greens - U21 v Eastern Lions - U21 | L | 4-1 |
| Ausztrál Victoria League - U21 | 2022/07/02 02:15 | Eastern Lions - U21 v Dél Melbourne - U21 | W | 4-3 |
| Ausztrál Victoria League - U21 | 2022/06/25 02:15 | Avondale - U21 v Eastern Lions - U21 | L | 1-0 |
| Ausztrál Victoria League - U21 | 2022/06/18 02:15 | Eastern Lions - U21 v Dandenong City - U21 | D | 2-2 |
| Ausztrál Victoria League - U21 | 2022/06/11 09:30 | Port Melbourne - U21 v Eastern Lions - U21 | L | 7-0 |
| Ausztrál Victoria League - U21 | 2022/06/04 02:15 | Eastern Lions - U21 v Altona Magic - U21 | D | 2-2 |
| Ausztrál Victoria League - U21 | 2022/05/27 08:15 | Oakleigh Cannons - U21 v Eastern Lions - U21 | L | 4-1 |
| Ausztrál Victoria League - U21 | 2022/05/21 02:15 | Eastern Lions - U21 v Dandenong Thunder - U21 | W | 4-0 |
| Ausztrál Victoria League - U21 | 2022/07/02 06:00 | Hume City - U21 v Melbourne Knights - U21 | L | 3-0 |
| Ausztrál Victoria League - U21 | 2022/06/25 05:00 | Melbourne Knights - U21 v St Albans Saints - U21 | D | 1-1 |
| Ausztrál Victoria League - U21 | 2022/06/19 03:00 | Heidelberg Utd - U21 v Melbourne Knights - U21 | W | 1-4 |
| Ausztrál Victoria League - U21 | 2022/06/10 08:15 | Bentleigh Greens - U21 v Melbourne Knights - U21 | L | 3-2 |
| Ausztrál Victoria League - U21 | 2022/06/04 05:00 | Melbourne Knights - U21 v Dél Melbourne - U21 | L | 2-4 |
| Ausztrál Victoria League - U21 | 2022/05/28 02:15 | Avondale - U21 v Melbourne Knights - U21 | W | 0-2 |
| Ausztrál Victoria League - U21 | 2022/05/21 05:00 | Melbourne Knights - U21 v Dandenong City - U21 | D | 1-1 |
| Ausztrál Victoria League - U21 | 2022/05/14 05:00 | Melbourne Knights - U21 v Port Melbourne - U21 | L | 0-1 |